Head to head
Which one will break you first?
Two fingerprints on one grid. Both are scored through your profile, so this answers the question for you rather than for the average player.
The Binding of Isaac: Rebirth is the harder of the two for you, by 0.4 points. The gap is widest on obscurity, where The Binding of Isaac: Rebirth asks considerably more than Age of Empires II: Definitive Edition. If you want the gentler run, start with Age of Empires II: Definitive Edition.
Axis by axis, biggest gap first
THE BINDING OF ISAAC: REBIRTH
A game about item literacy: the run is won or lost by whether you recognise a pickup you have never seen before.
Sustained pressure. Progress is earned.
AGE OF EMPIRES II: DEFINITIVE EDITION
Build orders are the curve, and the campaigns teach almost none of what the game actually asks for. The hard AI does not forget its economy while it fights.
Sustained pressure. Progress is earned.